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Sites with General
Information:
1.
The DigiBio
Site
Dr. Jacques Benveniste’s observations of what has come to be known
as «the memory of water» phenomenon, that is:
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that water
is capable of carrying molecular information (biological
messages), and
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that it is
possible to transmit and amplify this information, as can be done
for sounds and music”.
2. The Boiron Site
Ongoing
Research in Homeopathy and Immunology
1. The Biological
Action of Dilutions of Aspirin, Professor DOUTREMEPUICH (University
of Bordeaux, France)
In the past
ten years, studies have been conducted in the Hematology Department
of the School of Pharmacy of Bordeaux (France).
After having defined the validity and sensitivity of
this experimental model, the authors conducted a comparative study
on the effect of injecting several dilutions of aspirin.
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area of thrombus provoked by arteriolar lesion and
by venous lesion,
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number of emboli induced by arteriolar lesion and
by venous lesion,
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length of embolization period induced by arteriolar
lesion and by venous lesion,
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amplitude and speed of platelet aggregation (in
vitro).
2. The Synergistic
Effects of Dilutions of Antitumoral Agents
Professor BONAVIDA (UCLA, USA)
Professor
Bonavida's work consists in evaluating the toxicity of a certain
number of substances used at concentrations below those at which
their cellular toxicity has been demonstrated to date.
There are essentially four of these substances in question:
4. The Effect of
Dilutions of Antigens and Various Biologic Factors on the Activity
of Basophil Leukocytes
Dr. SAINTE-LAUDY (France), Professor MANNAIONNI (University of
Florence, Italy), Professor ENNIS (Queen's University, Belfast)
The action of
centesimal dilutions of various substances on several types of white
blood cells has been under study since 1981.
Polynuclear
basophils are studied most often…
After publication of an article on basophil
activation with high dilutions of anti-IgE, then the resultant
investigation, it became difficult to publish on the inhibition of
basophil activation with high dilutions.
4.
Center for Complex
Infectious Diseases
John Martin, M.D. Ph.D.
What are Stealth Viruses?
Viruses are submicroscopic infectious agents that replicate inside
cells. Viral illnesses are normally controlled by the body’s immune
system acting primarily through white blood cells called lymphocytes
Atypically-structured cell-damaging (cytopathic) viruses were
initially identified in patients with the chronic fatigue syndrome
and in patients with more severe neurological and neuropsychiatric
illnesses. The term “stealth” was introduced to highlight their
basic property of evading effective immune recognition, and also
because they had gone unrecognized by the medical community.
Published Scientific Papers:
1. Published
Research Projects in homeopathy:
Vittorio Elia and Marcella Niccoli
Thermodynamics of extremely diluted aqueous solutions.
Annals of the New York Academy of Sciences,
June 1999
An extensive thermodynamic study has been carried out on aqueous
solutions obtained through successive dilutions and succussions of
1% in weight of some solutes up to extremely diluted solutions,
(less than 1x10-5 mol kg-1) obtained via several 1/100 successive
dilution processes. The interaction of acids or bases with the
extremely diluted solutions has been studied calorimetrically at
25°C. Measurements have been performed of the heats of mixing of
acid or basic solutions, having different concentrations, with
bidistilled water or with the extremely diluted solutions. Despite
the extreme dilution of the solutions, an exothermic heat of mixing
in excess has been found, in about the 92% of the cases, with
respect to the corresponding heat of mixing with the untreated
solvent. Here [it is shown] that successive dilutions and
succussions may alter permanently the physical-chemical properties
of the solvent water. The nature of the phenomena here described
still remains unexplained, but significant experimental results are
obtained.
Dittmann and G. Harisch
Characterization of Differing
Effects Caused by Homeopathically Prepared and Conventional
Dilutions Using Cytochrome P450 2E1 and Other Enzymes as Detection
Systems
The journal of
Alternative and Complementary Medicine 1996 2:2,279-290.
Target of investigation was to ascertain differences in the effects
of homeopathic potencies (D) and equally concentrated conventional
dilutions (V) on p-nitrocatechol formation catalyzed by CYP
2E1. Arsenicum album and potassium cyanatum (D) were
compared to equivalent dilutions of As203 and KCN (V). Significant
differences in enzyme activity were found. The difference of
influence exists and this may be attributable to the manufacturing
process of homeopathic drugs, namely, the stepwise dilution with
intermediate agitation.
K. Linde, W.B. Jonas, D. Melchart, D., et al.,
Critical Review and Meta-Analysis
of Serial Agitated Dilutions in Experimental Toxicology
Human and
Experimental Toxicology, 1994, 13:481-92.
This meta-analysis of 105 studies in toxicology showed that
homeopathic medicines may be useful in treating toxic exposures.
This meta-analysis was conducted by a similar group of researchers
who recently published a meta-analysis on clinical studies in The
Lancet.
P.C. Endler, W. Pongratz, G. Kastberg, et al.,
The Effect of Highly Diluted Agitated Thyroxine on the Climbing
Activity of Frogs
Veterinary and
Human Toxicology, 1994, 36:56.
This, and the study below, show that a homeopathic medicine can
influence the growth and development of tadpoles in water.
P.C. Endler, W. Pongratz, R. van Wijk, et al.,
Transmission of Hormone Information by
Non-molecular Means
FASEB Journal, 1994, 8, Abs.2313.
This, and the study above, show that a homeopathic medicine can
influence the growth and development of tadpoles in water.
J. Benveniste, P.C. Endler and J. Schulte, (eds.),
Further Biological Effects Induced by
Ultra High Dilutions: Inhibition by a Magnetic Field," in Ultra High
Dilution
Dordrecht: Kluwer Academic,
1994, 35.
This, and the study below, show that certain magnetic fields can
neutralize the effects of a homeopathic medicine.
J. Benveniste, B. Arnoux, L.
Hadji,
Highly Dilute Antigen Increases Coronary Flow of Isolated Hart from
Immunized Guinea-pigs
FASEB Journal, 1992, 6:Abs.1610.
This, and the study above, show that certain magnetic fields can
neutralize the effects of a homeopathic medicine.
E. Davenas, B.
Poitevin, and J. Benveniste
Effect on Mouse Peritoneal Macrophages of Orally Administered Very
High Dilutions of Silica
European Journal of Pharmacology, April, 1987, 135:313-319.
This study showed Silica 6C and Silica 10C induced a statistically
significant increase in immune function, as measured in macrophages
in the blood of mice.
2.
Published Clinical Trials on the Efficacy of Homeopathic Medicine:
C. N. Shealy, MD, R.P. Thomlinson,
V. Borgmeyer,
Osteoarthritic Pain: A Comparison of Homeopathy and Acetaminophen
American Journal of Pain Management, 1998;8:89-91
A double-blinded study to document the relative efficacy of
homeopathic remedies in comparison to acetaminophen for the
treatment of pain associated with osteoarthritis (OA) among 65
patients. An IRB approved protocol. Results of the study documented
better pain relief in the homeopathic group (55% achieved measured
relief from homeopathy as compared to 38% from acetaminophen);
however, the superiority of this treatment, in comparison with the
acetaminophen group, did not reach statistical significance. The
investigators conclude that homeopathic treatments for pain in OA
patients appear to be safe and at least as effective as
acetaminophen, and are without its potential adverse effects
including compromise to both liver and kidney function. Many of the
patients asked to continue with the homeopathic treatment.
M. Weiser, W. Strosser, P. Klein,
Homeopathic vs. Conventional Treatment of Vertigo: A Randomized
Double-Blind Controlled Clinical Study
Archives of Otolaryngology--Head and Neck Surgery, August,
1998, 124:879-885.
This was a study with 119 subjects with various types of vertigo,
half of whom were given a homeopathic medicine (a combination of
four homeopathic medicines) and half were given a leading
conventional drug in Europe for vertigo, betahistine hydrochloride.
The homeopathic medicines were found to be similarly effective and
significantly safer than the conventional control.
D. Reilly, M. Taylor, N. Beattie,
et al.,
Is
Evidence for Homoeopathy Reproducible?
Lancet, December 10, 1994, 344:1601-6.
This study successfully reproduced evidence from two previous
double-blinded trials all of which used the same model of
homeopathic immunotherapy in inhalant allergy. In this third study,
9 of 11 patients on homeopathic treatment improved compared to only
5 of 13 patients on placebo. The researchers concluded that either
homeopathic medicines work or controlled studies don't. Their work
has again be recently replicated and is submitted for publication. (See
Is Homeopathy a Placebo Response? Lancet 1986, below.)
J. Jacobs, L. Jimenez, S. Gloyd,
Treatment of Acute Childhood Diarrhea with Homeopathic Medicine:
A Randomized Clinical Trial in Nicaragua
Pediatrics, May 1994, 93,5:719-25.
This study was the first on homeopathy to be published in an
American medical journal. The study compared individualized high
potency homeopathic preparations against a placebo in 81 children,
between ages 6 mo. and 5 yrs., suffering with acute diarrhea. The
treatment group benefited from a statistically significant 15%
decrease in duration. The authors noted that the clinical
significance would extend to decreasing dehydration and
postdiarrheal malnutrition and a significant reduction in morbidity.
E. Ernst, T. Saradeth, and K.L.
Resch,
Complementary Treatment of Varicose Veins: A Randomized
Placebo-controlled, Double-Blind Trial
Phlebology, 1990, 5:157-163.
This study of 61 patients showed a 44% improvement in venous filling
time in the homeopathic treated group when compared with placebo.
P. Fisher, A. Greenwood, E.C.
Huskisson, et al.,
Effect of Homoeopathic Treatment on Fibrositis
British Medical Journal, August 5, 1989, 299:365-66.
This trial was double-blind with a crossover design, comparing R
toxicodendron to a placebo in 30 patients all suffering from an
identical syndrome identified as the admission criteria. It showed a
significant reduction in tender spots, by 25%, when patients were
given the homeopathic medicine, as compared to when they were given
the placebo.
D. Reilly, M. Taylor, C. McSherry,
Is Homeopathy a Placebo Response? Controlled Trial of Homeopathic
Potency with Pollen in Hayfever as Model
Lancet, October 18, 1986, 881-86.
The double-blind study compared a high dilution homeopathic
preparation of grass pollens against a placebo in 144 patients with
active hay fever. The study method considered pollen counts,
aggravation in symptoms and use of antihistamines and concluded that
patients using homeopathy showed greater improvement in symptoms
than those on placebo, and that this difference was reflected in a
significantly reduced need for antihistamines among the
homeopathically treated group. The results confirmed those of the
pilot study and demonstrate that homeopathic potencies show effects
distinct from those of the placebo
He responded to these criticisms point by point.
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On the reproducibility of the phenomenon: a simple
protocol permitted confirmation of the inhibiting activity of
several dilutions of histamine, particularly 18 CH.
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On the subjectivity of the method: an automated
technique for measuring the activation of the basophils had been
developed, based on the expression of a "marker" for this
activation, determined by a flux cytometer. It recorded the
inhibiting activity of 17 and 18 CH of histamine.
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